The Eagles announced on Thursday that quarterback Jalen Hurts will not play against the Panthers due to a blood clot in his calf, which leaves Tanner McKee in line to make the first non-Week 18 start of his career.

McKee may have wide receiver DeVonta Smith available for the game. Smith has missed the last two games with a hamstring injury and he did not practice on Wednesday, but the team listed him as a limited participant in Thursday’s practice.

Wide receiver Dontayvion Wicks is moving in the opposite direction with his hamstring injury. Wicks was out of practice Thursday after working on a limited basis on Wednesday.

Running back Saquon Barkley (hamstring) remained out of practice and is on track to miss his second straight game. Defensive back Michael Carter (abdomen), linebacker AJ Epenesa (back), linebacker Jalyx Hunt (knee, ankle), and running back Will Shipley (foot) were also out on Thursday.

Cornerback Jakorian Bennett (knee), wide receiver Hollywood Brown (ankle), tight end Grant Calcaterra (back), guard Landon Dickerson (knee), linebacker Jonathan Greenard (ankle), tight end EJ Jenkins (toe), center Drew Kendall (knee), guard Tyler Steen (shoulder), and tight end Eli Stowers (quad) were the team’s limited participants.

Linebacker Zack Baun (shoulder), linebacker Jihaad Campbell (knee, wrist), defensive tackle Jalen Carter (wrist), linebacker Arnold Ebiketie (shoulder), safety Marcus Epps (groin), offensive tackle Fred Johnson (knee), and safety Andrew Mukuba (shoulder) were all listed as full participants.