The 49ers released defensive lineman Ogbo Okoronkwo on Friday, the team announced.
Okoronkwo played four games this season, with one start, and has two tackles and a sack.
He entered the NFL as a fifth-round pick of the Rams in 2018. Okoronkwo spent four seasons with the Rams (2018-21), one with the Texans (2022), two with the Browns (2023-24) and one with the Eagles (2025).
Okoronkwo, 31, has registered 134 tackles, 18 sacks, 41 quarterback hits, four passes defensed and four forced fumbles in his career.