LONDON -- Jacksonville Jaguars left tackle Anton Harrison will have arthroscopic surgery on his right knee when the team returns from London next week, league sources told NFL Network's Ian Rapoport and ESPN's Jeremy Fowler.

The team does not yet know the severity of the injury, which Harrison sustained during last Sunday's 19-17 victory over Philadelphia at Tottenham Hotspur Stadium. Depending on what surgeons find, Harrison could be out three to five weeks or the remainder of the regular season.

The Jaguars (4-1) play Houston (1-4) on Sunday at Wembley Stadium and are scheduled to fly back to Jacksonville after the game. Walker Little, who came in after Harrison's injury, is expected to start at left tackle.

Harrison was hurt while blocking on a running play, a sweep to the right by Bhayshul Tuten. Harrison appeared to grab his right knee after disengaging from a block and went down to the ground. He was eventually taken off the field on a cart.

Harrison, the 27th overall pick in 2023, was moved from right tackle to left tackle during training camp. He had missed just three games at right tackle in his first three seasons.

The Jaguars picked up Harrison's fifth-year option in April.