The New England Patriots (5-4) have officially placed running back TreVeyon Henderson on injured reserve ahead of their Week 10 matchup against the Detroit Lions (6-2) on Sunday at 9:30 a.m. ET on Fox in Munich, Germany.
NFL insider Tom Pelissero reported the roster move Saturday via X, formerly known as Twitter.
“The Patriots placed RB TreVeyon Henderson on injured reserve.”
The move will sideline Henderson for at least four games as New England prepares to face a Detroit team riding a four-game winning streak.
Henderson has appeared in six games this season, recording 203 rushing yards and one touchdown on 52 carries, averaging 3.9 yards per attempt. The 24-year-old has also contributed five receptions for 45 yards.
The second-year running back has struggled to replicate his impressive rookie campaign in 2025, when he rushed for 911 yards and nine touchdowns on 180 carries. He also added 221 receiving yards and another touchdown.
Patriots face running back concerns ahead of Lions matchup
Henderson's placement on injured reserve comes after he revealed earlier this month that he had been hospitalized while undergoing testing for unexplained neurological symptoms affecting his strength and coordination.
The former Ohio State standout has not played since New England's Week 7 loss to the Chicago Bears on Oct. 22. His recovery timeline remains uncertain.
The Patriots also activated fullback Reggie Gilliam and offensive lineman Greg Van Roten from injured reserve Saturday while elevating offensive lineman Andrew Rupcich from the practice squad.
New England enters Sunday's contest looking to bounce back from an embarrassing 45-27 loss to the Green Bay Packers in Week 9.
With Henderson sidelined, the Patriots will look to Rhamondre Stevenson, who is listed as questionable with a knee injury, to help lead their backfield against Detroit.