The 49ers will have star wide receiver Mike Evans for Monday Night Football.
Evans was questionable with ribs and Achilles issues, but he is active.
He has 24 catches for 326 yards and three touchdowns this season.
The 49ers will also have defensive lineman Mykel Williams (knee), cornerback Upton Stout (shoulder) and defensive back Siran Neal (neck). They, too, were questionable entering the game.
The 49ers’ inactives are defensive end Nick Bosa (knee, calf), offensive lineman Enrique Cruz, defensive lineman Naquan Jones, quarterback Kurtis Rourke, wide receiver Deebo Samuel (hamstring), safety Marques Sigle (ankle) and linebacker Garret Wallow (hamstring).
Washington will have wide receiver Stefon Diggs, who was questionable with a hamstring injury. He is active.
Diggs has 18 receptions for 170 yards and three touchdowns.
Cornerback Trey Amos (ankle) and safety Nick Cross (illness) are also active.
The Commanders’ inactives are quarterback Marcus Mariota, cornerback Fabian Moreau, cornerback Isaac Yiadom, outside linebacker T.J. Magunranyanga, offensive guard Tanoa Togiai and defensive end Charles Omenihu (groin, ankle).