Panthers outside linebacker Jaelan Phillips aggravated his hamstring in the first quarter.
The team lists his return as questionable.
Thomas Incoom replaced Phillips but was hurt while covering a punt on a blindside block by Feleipe Franks. He limped off the field.
Incoom is questionable to return with a calf injury.
Eagles outside linebacker Nolan Smith went into the training room without his helmet for an apparent concussion check. He appeared to be knocked out on a chip block by Chuba Hubbard in the second quarter.
The Eagles have only Jonathan Greenard, Arnold Ebiketien and Keyshawn James-Newby at the position.
The Panthers lead 3-0 on Ryan Fitzgerald’s 47-yard field goal.