Puka Nacua's hip injury headlines a banged-up Los Angeles Rams injury report ahead of Week 3, creating real fantasy uncertainty for one of the league's top wide receivers as the team travels to face the Broncos.
The Rams enter the week dealing with several notable absences and limitations, with the receiving corps and defensive front taking the brunt of the hits. Head coach Sean McVay's game plan could shift significantly depending on which players ultimately suit up Sunday, and fantasy managers need clarity before locking in lineups.
The final injury report of the week for the Rams and Broncos: pic.twitter.com/Bx2zoDXPmH
— Sarah Barshop (@sarahbarshop) September 25, 2026
Puka Nacua's Status Clouds WR1 Outlook

Nacua did not practice all three days this week and carries a doubtful tag into Sunday's matchup with a hip injury, making him a legitimate game-time decision at best for fantasy purposes. Losing Nacua would be a significant blow to the Rams passing attack, given his role as Matthew Stafford's primary target, and any manager rostering him should have a contingency plan ready.
If Nacua sits, expect a bump in target share for Davante Adams again who went off for 195 yards and two touchdowns on 10 receptions as Staffords WR1. Secondary options like Terrance Ferguson, Tutu Atwell, and Konata Mumpfield will need to step up as well.
Tight End Room Deals With Multiple Issues
Colby Parkinson did not practice at all this week because of a knee injury and is listed as questionable, while Terrance Ferguson battled through an ankle issue but improved to a full practice Friday with no game designation. Ferguson's clean bill of health by week's end makes him the safer bet at tight end, while Parkinson's total lack of practice reps raises real doubt about his availability.
Fantasy managers deep enough to roster either Rams tight end should lean toward Ferguson as the more trustworthy play, since Parkinson's questionable tag comes with almost no practice participation to lean on.
Secondary and Defensive Rest Days
Safety Kamren Kinchens is doubtful with a hamstring injury after failing to practice all week, which would be a loss for the Rams secondary but carries limited direct fantasy relevance outside of deeper IDP formats. His absence could mean more defensive snaps for depth pieces in the back end.
Defensive stars Aaron Donald and Byron Young were both held out of practice Friday for rest purposes rather than injury concerns, a “NIR” (not injury related) designation that suggests standard veteran maintenance rather than a lingering issue. Both remain candidates to suit up Sunday, and their potential availability matters for IDP and DST-focused fantasy formats given their impact on the pass rush.
Left tackle Alaric Jackson worked through a knee concern but progressed to full participation by Friday, carrying no game designation into Sunday. That's a positive sign for the protection in front of Stafford, since a compromised offensive line would create ripple effects across every skill-position player in the passing game.
Inside linebacker Nate Landman was limited in practice all three days with a shoulder injury but avoided a formal game designation, suggesting he's expected to play in some capacity even if not at full strength.
Fantasy Football Bottom Line
The clearest actionable takeaway is monitoring Nacua's status right up to kickoff, since his absence would meaningfully redistribute targets toward Whittington and second-year tight end Ferguson. Stafford's floor takes a hit without his top receiver, but the Rams passing offense retains enough talent to remain fantasy-relevant even in a diminished capacity.
Managers should treat Parkinson and Kinchens as risky plays given their lack of practice reps, while Jackson's clean recovery removes one layer of offensive line concern heading into the Denver matchup. Checking final inactives before locking lineups remains essential given how many game-time decisions dot this Rams injury report.

