Sunday Night Football in Week 3 presents to you the Los Angeles Rams (1-1) at the Denver Broncos (1-1) kicking off at 8:20 PM Eastern on NBC and Peacock! Denver and Los Angeles are both coming off wins as the defenses flexed its muscles holding opponents to 19 combined points last week. These are two of the best defensive squads in the NFL matching up at Mile High and they have to be feeling pretty good after getting in the win column for the first time in 2026.

The Rams handled the Giants, 28-6, as the stars were out for Los Angeles. Matthew Stafford threw for 327 yards and tossed four touchdowns, including two of them to Davante Adams who had a monster game. Adams caught eight passes for 195 yards and two touchdowns, while the LA running back duo of Kyren Williams (85 yards) and Blake Corum (79 yards) combined for 164 rushing yards on 24 carries. The defense had 10 pass deflections, one interception, held New York to 182 yards on 55 plays for 3.3 yards per play, and a 3-of-14 mark on third downs. Los Angeles did a 180 compared to the 27-7 season opening loss to the 49ers in Australia.

Denver’s Week 1 offensive issues carried over into the first half of Week 2 before Bo Nix and company finally got into the swing of things. The Broncos outscored the Jaguars 17-3 in the second half of Sunday’s 20-13 win over Jacksonville. Denver outgained Jacksonville, 392-268 in yards and averaged 1.7 more yards per play. The Broncos Offensive Coordinator, Davis Webb, received the criticism around the usage of Jaylen Waddle in Week 1. Waddle went from one reception and two yards on three targets to eight catches for 138 yards on 10 targets in Week 2! Rookie RB Jonah Coleman scored the first touchdown of his career against the Jaguars and Riley Moss nabbed his third career interception.

I think it’s safe to say that Denver versus Los Angeles will be a candidate for game of the week. Let’s dive into the numbers and see if we can’t find an additional sweat or two.

NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from DraftKings, player news and updates, and of course our predictions and best bets for the game from our staff of experts.

Game details and how to watch Rams at Broncos

· Date: Sunday, September 27, 2026
· Time: 8:20 PM ET
· Site: Empower Field at Mile High
· City: Denver, CO
· TV/Streaming: NBC | Peacock

NBC Sports is your home for all the latest updates on this matchup, featuring live odds, player news, expert analysis, and predictions.

Latest Game Odds for Rams at Broncos

The latest odds courtesy of DraftKings:

· Moneyline: Los Angeles Rams (-142), Denver Broncos (+120)
· Spread: Rams -2.5
· Total: 45.5

The opening spread for this game was Rams -3, so there’s support for Denver as a home underdog. The total hasn’t budged from 45.5.

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Expert picks & predictions for Rams at Broncos

Vaughn Dalzell (@VmoneySports) likes the Under 45.5:

“This will be one of the best games this weekend, but keeping it simple, these are two of the best defenses and they’re facing one another — Under 45.5 is the play. Both teams are 2-0 to the Under so far. Denver’s 20 points and comeback win over Jacksonville doesn’t solve their offensive woes, but it was a start. Los Angeles pummeled New York on Monday Night Football after losing in Australia. This is a lot of travel already for the Rams and in a higher altitude, a slow start could be possible. I like the Under 45.5 and might take a look at the first quarter Under if it reaches 10.5.”

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Rams at Broncos betting trends and stats

  • The Broncos and Rams are 1-1 ATS and 2-0 to the Under
  • Denver was 11-8 to the Under last year, ranking sixth-best
  • Los Angeles was 12-8 to the Over last year, ranking eighth-best
  • The Rams are 12-7 ATS as a favorite since the start of 2025
  • The Rams were 4-4 ATS as a road favorite in 2025 and 4-0 ATS in 2024
  • Denver is 4-2 to the Under and ATS as a home underdog since 2023
  • Denver was an NFL-best 3-0 ATS as a home underdog last year
  • The Rams are 14-11 ATS over the past 25 games following a win
  • The Broncos are 14-11 ATS over the past 25 games following a win

Quarterback matchup for Rams at Broncos

· Los Angeles: Matthew Stafford – Stafford had 155 yards, zero touchdowns and one interception in Week 1’s loss, then bounced back with four touchdowns, 327 yards, and one pick against the Giants. After 7 points in Week 1 and 28 points in Week 2, it appears the Rams are back on track, but without Puka Nacua, this offense will rely on clean football and their duo in the running game. Without Nacua, Davante Adams is filling in just fine as the No. 1 with eight catches, 195 yards, and two touchdowns versus New York.

· Denver: Bo Nix – Nix had a bounce back performance in the win over Jacksonville. The first half was shaky with three points, but Nix led three-straight scoring drives in the second half and iced the game on their fourth and final drive. Nix finished with 288 passing yards on 22-of-31 with one touchdown snd one intefetopion. Nix finally found some chemistry with Jaylen Waddle in their second game together. The former Dolphins receiver had eight receptions on 10 targets for 138 yards — almost half of Nix’s yards and completions.

Rams at Broncos Injury Update

  • Denver RB JK Dobbins (hamstring) is probable
  • Denver RB RJ Harvey (hamstring) is questionable
  • Denver WR Marvin Mims (foot) is questionable
  • Los Angeles WR Puka Nacua (hip/groin) is questionable
  • Los Angeles WR Jordan Whittington (quads) is questionable
  • Kamren Kinchens (hamstring) is questionable

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