Mike Vrabel and his squad make their way to international waters, as the New England Patriots take on the Detroit Lions in Munich, Germany, on Sunday at 9:30 a.m. ET. It is time to continue the NFL odds series with a Patriots-Lions prediction and pick.

New England enters the game sitting at 5-4. They suffered a tough 1-2 start, losing to the Seattle Seahawks and the Jacksonville Jaguars while beating the Pittsburgh Steelers. New England gained some momentum following three consecutive wins over the Buffalo Bills, the Las Vegas Raiders and the New York Jets. However, they have since lost two of their last three contests, falling to the Chicago Bears and the Green Bay Packers while taking down the Miami Dolphins in between.

Meanwhile, Detroit has a 6-2 record. They started the season with a 31-30 win over the New Orleans Saints in Week 1. They lost in a 41-31 shootout to the Bills before bouncing back with a 31-24 win over the Jets. After falling 32-26 to the Carolina Panthers, they have since strung together four consecutive victories over the Arizona Cardinals, the Packers, the Minnesota Vikings, and the Dolphins.

Odds provided by BetOnline

Patriots vs. Lions Odds

Patriots: +2.5 (-105)

Lions: -2.5 (-115)

Over: 49.5 (-115)

Under: 49.5 (-105)

Patriots vs. Lions Key Injuries

Patriots- S Kevin Byard III (Questionable), TE Hunter Henry (Injured), OG Greg Van Roten (Questionable), OT Morgan Moses (Injured), CB Carlton Davis III (Out), WR AJ Brown (Questionable), C Ben Brown (Out), S Brendan Schooler (Questionable), FB Reggie Gilliam (Questionable), TE Cameron Latu (Questionable), RB Rhamondre Stevenson (Questionable), CB Charles Woods (Questionable), OG Walter Rouse (Questionable), QB Drake Maye (Injured), RB TreVeyon Henderson (Out)

Lions- C Cade Mays (Out), CB DJ Reed (Out), RB Sione Vaki (Questionable), CB Brian Branch (Injured), QB Jared Goff (Injured), S Kerby Joseph (Out), WR Amon-Ra St. Brown (Questionable), RB Jacob Saylors (Injured), DL DJ Wonnum (Injured)

Patriots vs. Lions Betting Trends

  • Over is 6-0 in Patriots last 6 games overall.

  • Over is 6-0 in Patriots last 6 games after allowing more than 30 points in their previous game.

  • Over is 5-0 in Patriots last 5 games after allowing more than 350 total yards in their previous game.
  • Over is 5-0 in Patriots last 5 games following a straight up loss of more than 14 points.
  • Under is 4-1 in Lions last 5 games on grass.
  • Over is 3-0-1 in Lions last 4 games in Week 10.

Keys to Patriots vs. Lions matchup

The Patriots' offense will have plenty of chances to find holes in the Lions' defense. Drake Maye is going through a tough third year in the NFL following an incredible sophomore campaign, but he is still capable of delivering a strong game in this offense. He completed 65.4% of his passes for 2,282 yards and 18 touchdowns and 11 interceptions while rushing 47 times for 219 yards and three touchdowns. Rhamondre Stevenson leads all rushers with 102 carries for 399 yards and two touchdowns while catching 26 passes for 258 yards and two touchdowns. Demario Douglas tops receivers with 434 yards and four touchdowns on 31 catches, while Hunter Henry comes next with 32 receptions for 361 yards and two touchdowns.

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New England's defense will seek to be explosive with their playmaking against Detroit's offense, especially when Jared Goff throws the ball into coverage. Christian Elliss leads that side of the ball with 65 tackles, 1.5 sacks, one pass deflection, and one forced fumble. Marcus Jones has shined in the secondary with 47 tackles, six pass deflections, three TFL, one sack, and one interception. Kevin Byard has been productive with 43 tackles and three pass deflections, while Elijah Ponder racks up 25 tackles, 9.5 TFL and 7.5 sacks to his name.

The Lions boast one of the best offenses in the entire league, hoping to make a quick return to the playoffs after missing out last season. Jared Goff has been relatively healthy as he looks to put together another efficient showing as a passer. He has completed 67.8% of his passes for 2,134 yards and 15 touchdowns and two interceptions while rushing 19 times for 20 yards and a touchdown. Jahmyr Gibbs has shined as arguably the best running back in the league this season, racking up 177 carries for 847 yards and nine touchdowns while catching 34 passes for 285 yards and two touchdowns. Amon-Ra St. Brown is the heart of the receiving game with 61 catches for 657 yards and five touchdowns, while Jameson Williams assists him with 28 receptions for 468 yards and five touchdowns.

The Lions will be busy trying to hold off New England's offense, especially in the air. Jack Campbell leads that side of the ball with 57 tackles, one TFL, and one fumble recovery. Chuck Clark comes next with 49 tackles, three pass deflections, two interceptions, and one sack. DJ Reed shines in the secondary with 42 tackles, seven pass deflections, three TFL, and one interception. Meanwhile, Derrick Barnes and Aidan Hutchinson excels with their pass rushing by combining for 59 tackles, 12 TFL, eight sacks, and a forced fumble.

Patriots vs. Lions Prediction and Pick

This matchup between the Patriots and the Lions stands out as an intriguing matchup. New England needs serious momentum by beating one of the best performing teams in the NFL. As for Detroit, they need a strong defensive performance against a creative offense capable of giving them fits throughout the contest. Nonetheless, German fans will be in for a treat between two solid squads. The Patriots get the win in this one, while the under also hits.

Final Patriots vs. Lions Prediction and Pick: Patriots +2.5 (-105) and under 49.5 (-105)