It is a Top 25 matchup in the SEC as Ole Miss tries to keep rolling when they visit Florida. It is time to continue the NCAA Football odds series with an Ole Miss-Florida prediction and pick.
Ole Miss comes into the game at 3-0. It was not a perfect first game of the year, facing Louisville. Ole Miss allowed Louisville to score 14 points in the fourth quarter to tie the game. Still, the Rebels drove the field and kicked a game-winning field goal, taking the 41-38 victory. Ole Miss then took out Charlotte 41-9. Last time out, the Rebels faced off against LSU and former head coach Lane Kiffin. The Rebels had a 24-7 lead heading into halftime, but LSU would tie the game in the fourth quarter. The team scored on a Trindiad Chambliss touchdown to take the lead, and then Ole Miss sealed the game with an interception, taking the 32-24 victory.
Meanwhile, Florida is also 3-0 this year. After a 66-21 victory over FAU, the Gators took a 52-3 victory over Campbell. Last week, they hit the road for the first time, visiting Auburn. It was a tight first half, with Florida hitting a field goal at the end of the half to take the 20-17 lead. The Gators took over from there, scoring two quick touchdowns to open the half. Jadan Baugh was dominant in the game, running for 162 yards and three touchdowns, on the way to a 44-39 victory. This is the first time Florida is 3-0 since 2019, when they would get to 6-0 before losing to eventual national champion LSU.
This will be the 28th meeting between Ole Miss and Florida. Each team has won 13 times, and there has been a tie as well. Ole Miss took the win in 2025, winning 34-24. The Rebels have not won in the Swamp since 2008, when Ole Miss won 31-30.
Ole Miss vs. Florida Odds
Ole Miss: +3 (-105)
Florida: -3 (-115)
Over: 58.5 (-115)
Under: 58.5 (-105)
Watch Ole Miss-Florida LIVE with fuboTV (free trial)Ole Miss vs. Florida Key Injuries
Ole Miss- RB Kewan Lacy (Questionable), LB Keaton Thomas (Probable), OL Tommy Kinsler (Probable), OL Delano Townsend (Probable)
Florida- WR Eric Singleton Jr. (Questionable), DE Emmanuel Oyebadejo (Questionable), RB Evan Pryor (Questionable)
Ole Miss vs. Florida Betting Trends
– Ole Miss has covered just once in three games this year.
– The Rebels not only covered but won outright in their only game as the underdog.
Article Continues Below– The over has hit just once in three games for Ole Miss
– Florida has covered in two of their three games this year, including their only game as a favorite of under a touchdown.
– The over has hit in two of three games for Florida this year.
– Each team has covered four times in their last eight games agaisnt each other.
Keys to Ole Miss vs. Florida matchup
Ole Miss could be without Kewan Lacy due to an injury. Lacy has run for 191 yards and four touchdowns this year, and while Pete Golding is confident in the other backs, not having him will put a lot of pressure on Trindiad Chambliss. Chambliss has been great this year, completing 77 of 110 passes for 924 yards. He has also thrown for seven touchdowns and run for two. Chambliss has been picked just twice this year. The secondary for the Gators can be attacked and has shown some vulnerabilities. Chambliss will need to find Deuce Alexander and Traylon Ray in this one. Alexander has brought in 20 catches for 295 yards and three touchdowns. Meanwhile, Ray has 171 yards and a touchdown this year.
On defense, Ole Miss needs to focus on Jadan Baugh. He has already run for 458 yards and eight touchdowns this year. Ole Miss has not been great against the run this year, giving up 159 yards per game, which is 85th in the nation. Meanwhile, Florida is the fifth-ranked rushing attack in the nation. Because of the lack of a run defense, teams have been able to convert well on third downs, with short opportunities. If Ole Miss allows Florida to have short third downs, it is going to put a lot of pressure on the front seven of the Rebels.
For the Gators, the offense just needs to keep on schedule, something they have done well all year. They are second in the nation in points per game and first in yards per game. They are also averaging 7.7 yards per play and have been perfect in the red zone. Keeping ahead of the chains starts with Baugh, but if Baugh is running well, Aaron Philo will also be in a solid situation. He has completed 47 of 64 passes so far this year for 721 yards. HE also has six touchdowns, while running in two touchdowns.
On defense, Florida needs to put pressure on Chambliss. Currently, Florida has one of the best pass rushes in the nation, already having 11 sacks this year. This is led by Jayden Woods, who has three sacks. Meanwhile, Emmanuel Oyebadejo has 2.5 sacks this season. The Rebels have done a solid job of protecting Chambliss, but if Lacy is out in this game, the line will be under more pressure with the possibility of a diminished running game. If the Gators can slow down the running game of Ole Miss and unleash their solid pass rush, it could be a long day for the Rebels' offense.
Ole Miss vs. Florida Prediction and Pick
Florida comes into the game as the favorite, something that surprised Gators head coach Jon Sumrall. Home-field advantage for the Gators is playing into this line, and Ole Miss is also coming off a highly physical road win. The Florida front seven has been able to create pressure even without blitzing, which will limit the time Chambliss has to pass and find receivers deep downfield. If Lacy is limited or does not play, there is even more pressure on the quarterback. While Florida is playing well, the best player on the field plays for Ole Miss. Chambliss has consistently found a way to win and will do it again in this one.
Final Ole Miss vs. Florida Prediction and Pick: Ole Miss +3 (-105) and Over 58.5 (-115)