The NFL Least kicks off Week 10 with a “battle” between the Washington Commanders and New York Giants, two teams that gave us one of the dumbest ties in NFL history last time they got together. It may not be pretty, but it should be fun to watch for the neutral fan. So, with that as the opener, let’s jump right into the ClutchPoints NFL Week 8 picks, predictions, and odds column.
The 2026 NFL trade deadline has come and gone, and there are some teams that are materially different heading into Week 10. The Jacksonville Jaguars, Minnesota Vikings, Buffalo Bills, Kansas City Chiefs, and San Francisco 49ers all added pieces that could help them make a Super Bowl run.
On the flip side, franchises like the Indianapolis Colts, Philadelphia Eagles, and Tennessee Titans seemed to have packed it in for the year and are already on to the offseason for all intents and purposes. That could lead to some lopsided scores or real surprises moving forward.
As we look at the Week 10 calendar, we welcome back the Pittsburgh Steelers, Tennessee Titans, and say goodbye for a week to the Chicago Bears, Denver Broncos, Philadelphia Eagles, and Tampa Bay Buccaneers.
For the NFL Week 9 slate, we start with a Thursday nighter, followed up by an international matchup from Munich, Germany, at 9:30 am ET. We then get seven early-window Sunday games, just three late-window showdowns, a Sunday night tilt, and a Monday night affair.
The ClutchPoints NFL picks, predictions, and odds column had another winning weekend, posting a 12-3 record straight up and going 9-6 against the spread. That brings us to 84-52 (61.7%) straight up and keeps us on the winning side overall at 69-63-4 (52.2%) ATS thus far.
Previous weeks: Week 1 | Week 2 | Week 3 | Week 4 | Week 5 |Week 6 | Week 7 | Week 8 | Week 9
So, let’s get right into the NFL Week 10 picks, predictions, and odds.
Courtesy of DraftKings, here are the NFL odds.
Washington Commanders at New York Giants (-1.5)
The Giants are only a slight public pick, taking in about 51% of the bets right now. That could change, so the fading the public in prime-time games strategy won’t work here. What does work for us, though, is that the Giants are pretty decent with J.J. McCarthy under center, and the Commanders stink strategy.
The last time these two teams got together, it ended in an ugly tie. This time, they are franchises headed in opposite directions during the 2026 season. The G Men are making their case to at least be a playoff team, while it’s back to the top of the draft for the artist formerly known as the Washington Football team.
Pick: Giants 17-14
New England Patriots at Detroit Lions (-2.5)
This game being in Germany obviously makes it a little harder to pick than most stateside games. New England looked bad last week against the Packers, and now they face another tough NFC North team. Mike Vrabel and Drake Maye have been good after losses in their time together, but this feels a little different.
The Lions aren’t perfect, but when they are only favored by a field goal or so, they usually come through with the cover. Ultimately, we’re going to go with Jared Goff, Jahmyr Gibbs, and the (somewhat boring) consistency of the Lions over the ebbs and flows of the Patriots.
Pick: Lions 30-24
Minnesota Vikings at Green Bay Packers (-3.5)
Kirk Cousins is back, baby, and the Vikings travel to Wisconsin to take on Jordan Love and the Packers. Green Bay is hot, at home, and has the rest advantage, so there are plenty of reasons that the smart money is probably on the Packers.
However, there should be a new QB bump for this Vikings defense, which was beaten down and demoralized more by Carson Wentz than Josh Allen on Monday. Minnesota is the better team all around here, and once they get their at least league-average signal-caller in the door, they should show Green Bay the talent disparity.
Pick: Vikings 21-20
Houston Texans (-4.5) at Cleveland Browns
The Browns didn’t have a sell-off at the NFL trade deadline, but after losing to the Saints last week, their season is on life support at 5-4. The Texans, on the other hand, have won three of their last four and are starting to look like the playoff team most analysts thought they’d be before the season.
From those perspectives, this seems like a no-brainer, which is why the public is hugely on the visiting team. However, the Browns have been excellent at home of late, at least when it comes to covering the spread. That means here, we will take the Texans to win, but expect the Browns to make it competitive and cover.
Pick: Texans 16-14
Kansas City Chiefs (-3.5) at Atlanta Falcons
The Falcons have been terrible at home this season, and the Chiefs are one of the teams that should get some extra wind in its sails after making the NFL trade deadline deal for Josh Downs. We’re not convinced Downs solves all KC’s problems, but he’s an upgrade for now.
The Chiefs are the biggest public team on the board this week, and with good reason. So, while the ClutchPoints NFL picks, predictions, and odds column does love a good public fade, with this one we’re going to give the points and expect Patrick Mahomes and company to take care of business.
Pick: Chiefs 28-12
Miami Dolphins at Indianapolis Colts (-3.5)
Welcome to the Somebody Has to Win Bowl! The Dolphins have struggled all season but were frisky at times. Now they are without Malik Willis and will start Kyle McCord at quarterback. The Colts players who are left return to a team that wasn’t very good with all their star players, and now half of them are gone.
This game should be pretty much unwatchable, but we make every pick here at the ClutchPoints NFL picks, predictions, and odds column. That means we have to handicap this awful game. Give us the Dolphins to cover and, what the heck, even pull off the upset. We’ll take the points and the unknown QB over the bad team we know all too well.
Pick: Dolphins 14-13
Carolina Panthers at New Orleans Saints (-2.5)
This is yet another ugly NFC South matchup where, frankly, neither team will likely deserve to win. That said, one of these teams will walk away with the W, so let’s try and figure out which one comes out on top.
And after careful study and deliberation, we have no idea what is going to happen here. What we do know is that the Saints haven’t been great at home of late, yet they are the favorite. And for that reason alone, we’ll take the Panthers to pull the upset.
Pick: Panthers 23-22
Jacksonville Jaguars (-10.5) at Tennessee Titans
Big spreads have not come through all that often in the 2026 season, but this game may be an outlier where the double-digit favorite will cover. And that goes beyond the Jaguars making a ton of winning moves at the deadline and just being one of the best teams in the league while the Titans stink.
Robert Saleh is 8-18 against the spread in Week 10 or later in his coaching career. Whether that is on him or on his franchises trading away his best players, the stat is the stat. Now that Jeffery Simmons and Amani Hooker are gone, this defense is going to be terrible, and the Jags will take advantage of that.
Pick: Jaguars 33-13
Buffalo Bills (-7.5) at New York Jets
We’re going to go ahead and take the Bills to win and cover here. Yes, Josh Allen and company are always good for a complete meltdown against a poor divisional opponent, but with the Jets allowing the most points in the league the last two weeks, the Bills should be able to outscore them.
Additionally, Buffalo added Amani Hooker at the 2026 NFL trade deadline, and he is expected to play on Sunday. Look for the safety to make at least one big play for his new team, and that will help the Bills beat the Jets by more than a touchdown.
Pick: Bills 34-22
Los Angeles Rams (-9.5) at Arizona Cardinals
We here at the ClutchPoints NFL picks, predictions, and odds column are Carson Beck supporters, so while it wasn’t the smoothest transition from third stringer to starter (with a QB trade and an injury needed to get him there), the Cardinals finally have a young signal-caller who may be able to offer a glimpse of hope in an otherwise dark season.
You know we like big spreads here this season, and the Rams have been capable of putting up stinkers when they should win big this season. Add all that to a little new, young QB bump, and we like the Cards to at least put up a fight and lose by a touchdown or less.
Pick: Rams 23-16
Seattle Seahawks (-6.5) at Las Vegas Raiders
The biggest Wild Card here is Fernando Mendoza. Can the rookie QB come out in his first start and lead the Raiders to victory? That is hard to see against a Seahawks defense that is among the best in the league.
No. 1 overall picks don’t often win their debut, although Caleb Williams recently bucked that trend. In this one, we don’t expect Mendoza to win either, but with the good-sized spread and some talent around him at home, we can absolutely see this one being close.
Pick: Seahawks 26-23
San Francisco 49ers (-4.5) at Dallas Cowboys
The 49ers are the much better team here, so it’s not surprising they are the favorites on the road. And when you take into account that Brock Purdy has owned Dak Prescott in his career—3-0 both straight up and against the spread—this becomes a no-brainer.
The public is definitely heavy on this one, but in a week with a ton of lopsided matchups, there are several games the average bettor is in on more. We’re not worried about any of that, though, as the 49ers are a Super Bowl contender and the Cowboys are decidedly not at this point.
Pick: 49ers 35-27
Pittsburgh Steelers at Cincinnati Bengals (-3.5)
In a tough NFC North, there is little to distinguish the Steelers and Bengals. Both are capable of playing excellent, balanced football, and each has an elite unit with the Pittsburgh D and the Cincinnati offense. This game should go down to the wire.
Because this game should be close and the Bengals are giving more than a field goal, the ClutchPoints NFL Week 8 picks, predictions, and odds column likes Pittsburgh. Add the fact that the Steelers are coming off a bye and teams with the rest advantage are doing exceedingly well in 2026, and we’ll pick the upset here, too.
Pick: Steelers 18-16
Los Angeles Chargers at Baltimore Ravens (-4.5)
While the Ravens keep getting more and more banged up, the Chargers just get worse and worse with no real rhyme or reason other than the fact that they stink. They can’t even get a trade right, as linebacker Daiyan Henley was returned to sender by the Denver Broncos.
We said last week that we were going to keep riding the Chargers to lose until they proved us wrong. Playing the Ravens this week makes this tough, but we are going to stick to our guns here. Baltimore now has Jacoby Brissett, and the public is all over the Chargers in a prime-time game, which has often been the kiss of death in 2026. It isn’t easy to pick the Ravens to cover more than a field goal here, but we believe in the Chargers’ terrible-ness!
Pick: Ravens 26-19