Lane Kiffin and his squad make their way to Alabama, as the No. 18 LSU Tigers visit the Auburn Tigers on Saturday afternoon at 12 p.m. ET. It is time to continue the NCAA Football odds series with an LSU-Auburn prediction and pick.

LSU enters the game sitting at 5-2. They opened the season with a dominant 51-10 win over the Clemson Tigers. After a 45-14 blowout win over Louisiana Tech, they took a step back after falling 32-24 to the then-No. 8 Ole Miss Rebels. They bounced back with wins over No. 23 Texas A&M 35-6 and McNeese (63-14) then fell down to earth with a 35-34 upset loss to the Kentucky Wildcats before recovering with a dominant 31-0 shutout win over the then-No. 16 Mississippi State Bulldogs.

Meanwhile, Auburn has a 4-2 record. They started the season with a 17-16 win over the Baylor Bears in Week 1. They went on to secure a blowout win over the Southern Mississippi Golden Eagles (43-8) before falling to the Florida Gators 44-39. Auburn got a 21-15 win over the Vanderbilt Commodores then lost 24-14 to the then-No. 17 Tennessee Volunteers before bouncing back with a 27-24 upset win over the then-No. 1 Georgia Bulldogs.

LSU and Auburn share a long history of playing against each other in football. The former boasts 30 wins over Auburn's 24 victories while they drew once. LSU took the win back in October 2023, winning the game 48-18. LSU has won five of the last seven contests dating back to 2017.

Odds provided by BetOnline

LSU vs. Auburn Odds

LSU: -7 (-108)

Auburn: +7 (-112)

Over: 51.5 (-110)

Under: 51.5 (-110)

LSU vs. Auburn Key Injuries

LSU- TE Trey'Dez Green (Questionable), S Dashawn Spears (Out), RB Raycine Guillory Jr. (Questionable), WR Phillip Wright III (Out), WR Tre'Brown (Questionable), LB Tylen Singleton (Questionable)

Auburn- TE Hunter Herring (Questionable), WR Erick Smith (Out), RB Nykahi Davenport (Out)

LSU vs. Auburn Betting Trends

  • Under is 11-1 in the last 12 meetings in Auburn.
  • Under is 6-1 in Auburn's last 7 games as a home favorite.

  • Over is 8-2 in LSU's last 10 games as a road favorite.
  • Under is 5-1 in Tigers last 6 games after allowing more than 280 yards passing in their previous game.
  • Under is 6-1 in Tigers last 7 games after accumulating less than 170 yards passing in their previous game.

Keys to LSU vs. Auburn football matchup

The LSU Tigers possess one of the best offenses in the country, shining as a fierce squad in Year 1 under Lane Kiffin so far. They rank seventh in the country with 504 yards per game, eighth in passing offense with 307.9 yards per game, 32nd in rushing offense with 196.1 yards per game, and seventh in scoring offense with 40.4 points per contest. Sam Leavitt stands out with his dual threat talents at quarterback, throwing for 1,785 yards and 14 touchdowns and eight interceptions while rushing 64 times for 270 yards and seven touchdowns. Dilin Jones leads the run game with 128 carries to his name for 566 yards and five touchdowns. Jackson Harris leads receivers with 456 yards and five touchdowns on 27 catches, while Winston Watkins Jr. caught 33 passes for 447 yards and two touchdowns.

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LSU also shines as an elite squad on the defensive side of the ball. They rank fourth in yards allowed with 256.6 yards per game, 17th in passing defense with 168.3 yards per game, 11th in rushing defense with 88.3 yards per game, and 17th in scoring defense with 15.9 points per contest. TJ Dottery leads the unit with 52 tackles, three pass deflections and two forced fumbles. Princewill Umanmielen has been remarkable as a pass rusher with 30 tackles and eight sacks, while Jordan Ross has a pick-6 touchdown to his name with 19 tackles to go with it.

The Auburn Tigers have serious momentum after stunning No. 1 Georgia, earning votes in the AP Top 25. Auburn ranks 67th in the nation with 393.7 yards per game, 91st in passing offense with 211.7 yards per game, 46th in rushing offense with 182 yards per game, and 84th in scoring offense with 26.8 points per game. Byrum Brown continues to flourish as a dual threat quarterback with 1,205 yards and eight touchdowns and seven interceptions while rushing 107 times for 459 yards and five touchdowns. Jeremiah Cobb produces in the run game with 58 carries for 306 yards and two touchdowns, while Keshaun Singleton and Chas Nimrod are active in the receiving game. Singleton leads with 32 catches for 367 yards and two touchdowns, while Nimrod has 31 receptions for 333 yards and three touchdowns.

Auburn showcases itself to be balanced as a defensive squad despite not having an elite status like LSU. They rank 87th nationally with 371 yards allowed per game, 96th in passing defense with 228 yards per game, 74th in rushing defense with 143 yards per game, and 54th in scoring defense with 21.8 points per game. Elijah Melendez has excelled as a pass rusher and even in the secondary by racking up 52 tackles, five pass deflections, four sacks, and an interception. Xavier Atkins comes next with 37 tackles and three sacks, while Cody Sigler has 18 tackles and two forced fumbles.

LSU vs. Auburn Prediction and Pick

This matchup between LSU and Auburn stands out as an intriguing matchup. It's a battle of the Tigers as both squads have significant momentum while attempting to build their cases for the College Football Playoff. However, Auburn has an overreliance on Byrum Brown producing on the ground and in the air. It will be a long day for them if Brown can't get going early, resulting in LSU having the upper hand in convincing fashion. Both offenses will be active throughout the day, but only one will emerge victorious. LSU gets the win in this one and covers, while the over also hits.

Final LSU vs. Auburn Prediction and Pick: LSU -7 (-108) and over 51.5 (-110)