
Our Liverpool vs Tottenham Hotspur predictions look ahead to the third-round clash at Anfield, where one of these two Premier League heavyweights will be eliminated from the competition.
Liverpool vs Tottenham Hotspur head to head overview
- Date: Tuesday 15th September.
- Kick-off: 8pm.
- Venue: Anfield, Liverpool, England.
- Where to watch: ITV4 and ITVX, Sky Sports Main Event and Sky Sports Football.
Liverpool vs Tottenham Hotspur quick tips
- Liverpool to win - 3/4 with Midnite
- Liverpool to win the first half to nil - 8/5 with Betway
- Alexander Isak to score any time - 6/5 with SBK
Liverpool vs Tottenham Hotspur predictions
Liverpool and Tottenham Hotspur have both endured frustrating starts to the new season.
The Reds were held to a 0-0 draw by Fulham at the weekend, meaning they have won just one of their first four Premier League fixtures in 2026/27.
TottenhamâÂÂs record is even worse. They too were involved in a scoreless stalemate at the weekend, drawing 0-0 with Everton - a result which moved them onto two points from a possible 12.
This meeting on Tuesday gives both teams the chance to boost their confidence ahead of the final round of Premier League fixtures before the extended international break.
The EFL Cup offers Liverpool and Spurs a potential route to silverware this term, so neither Andoni Iraola nor Roberto De Zerbi should turn their nose up at this tournament.
Liverpool have had more to cheer so far this term, but there have been a few teething problems as Andoni Iraola gets to grips with the job.
There are clearly holes in the squad too, with question marks over the defence and the midfield. Florian Wirtz, meanwhile, continues to flatter to deceive.
As for Tottenham, a summer spending spree has yet to improve on-field results. De Zerbi is not under pressure yet, but he needs results to turn sooner rather than later.
Liverpool vs Tottenham Hotspur tips
Liverpool and Tottenham Hotspur will face off in the EFL Cup on Tuesday night.
Reds to bounce back
Liverpool underwhelmed in the 0-0 draw with Fulham last time out, but this will be a different type of game.
Fulham had been open defensively in their first few outings of the campaign, but they dug in well at the weekend. A Roberto De Zerbi team is unlikely to adopt the same sort of defence-first approach.
That should suit Liverpool, who have looked their most dangerous this season when they are given space in which to play.
Tottenham Hotspur are low on confidence right now and the fact Liverpool are playing at home is another factor in their favour.
â½ Tip Liverpool to win at 3/4 with Midnite â½
Spurs struggling in attack
Roberto De Zerbi is an attack-minded manager. When his teams click, they are capable of playing some fantastic football.
We have seen little evidence of that at Tottenham Hotspur, however. They were very flat in the goalless draw with Everton on Saturday.
Liverpool have not been entirely convincing defensively, but TottenhamâÂÂs frontline has posed too little a threat to opposition backlines up to now.
The Reds should get to half-time without conceding, and we like their chances of finding the back of the net in the opening 45 minutes too.
â½ Go for Liverpool to win the first half to nil at 8/5 with Betway â½
Isak on target?
Florian Wirtz had a tough debut campaign at Liverpool and we are yet to see signs of an upturn in 2026/27.
It is still early days, of course, but Wirtz is struggling to influence games and he could be rotated out of the starting XI here.
It has been easier to spot positives in Alexander IsakâÂÂs early performances this term. He is not yet back to his best, but the Sweden international certainly looks sharper than he did last season.
Provided he starts, there is a good chance Isak will make the net bulge in this one.
â½ Back Alexander Isak to score any time at 6/5 with SBK â½
Liverpool vs Tottenham Hotspur predicted lineups
- Liverpool expected lineup: Mamardashvili; Frimpong, Jacquet, Van Dijk; Tsimikas; Gravenberch, Mac Allister; Munoz, Szoboszlai, Gakpo; Isak.
- Tottenham Hotspur expected lineup: Kinsky; Gray, Van Hecke, Senesi, Robertson; Gray, Gallagher; Savinho, Maddison, Tel; Marmoush.
Liverpool vs Tottenham Hotspur latest odds
Find the latest Liverpool vs Tottenham Hotspur betting odds here. All odds are provided by our recommended football bookmakers and are subject to change.
- Liverpool: 3/4 with Midnite
- Draw: 11/4 with Betway
- Tottenham Hotspur: 16/5 with SBK
More EFL Cup predictions
We have plenty more EFL Cup predictions and picks - find our latest betting tips from expert punters in our match preview overview.
Important historical facts about Liverpool vs Tottenham Hotspur for betting
Tottenham Hotspur have only won one of their last seven games against Liverpool in all competitions. Liverpool beat Tottenham Hotspur in the semi-finals of the EFL Cup in 2024/25.
- Last meeting: 15th March 2026; Liverpool 1-1 Tottenham Hotspur.
- Last 6 matches: Liverpool wins - 4; Tottenham Hotspur wins - 1; Draws - 1.

Greg Lea
Greg Lea is a freelance football writer from London. He predominantly covers the Premier League and has had work published by the Guardian, FourFourTwo, ESPN and others.
Follow Greg on X: @GregLeaFootball
Commercial content notice: Taking one of the bookmaker offers featured in this article may result in a payment to talkSPORT. 18+. T&Cs apply.
Remember to gamble responsibly
A responsible gambler is someone who:
- Establishes time and monetary limits before playing
- Only gambles with money they can afford to lose
- Never chase their losses
- DoesnâÂÂt gamble if theyâÂÂre upset, angry or depressed
- Gamcare âÂÂàwww.gamcare.org.uk
Find ourÃÂ detailed guide on responsible gambling practices here.
For help with a gambling problem, call the National Gambling Helpline on 0808 8020 133 or go toÃÂ www.gamstop.co.ukÃÂ to be excluded from all UK-regulated gambling websites.

