Lamar Jackson started for the first time since Oct. 4, missing the past three games with a high ankle sprain. He lasted one play against the Bills.
The Ravens quarterback injured his right thumb and is questionable to return.
Jackson took a hard hit on an incompletion intended for Zay Flowers and immediately left the field. The team’s medical staff took him to the X-ray room.
Tyler Huntley has replaced Jackson.
The Bills lead 10-0, having scored on both of their drives.
Josh Allen scored his 88th career rushing touchdown on a fourth-down quarterback sneak, and Tyler Bass kicked a 56-yard field goal.