EAST RUTHERFORD, N.J. -- New York Jets quarterback Geno Smith suffered an ankle injury in the third quarter of Sunday's game against the Buffalo Bills and was replaced by rookie Cade Klubnik at MetLife Stadium.

Smith walked gingerly to the sideline after getting knocked down by Bills safety Cole Bishop on an incomplete pass with 4:26 remaining in the quarter. Smith went to the medical tent and then to the locker room, ending his day.

The Jets made a field goal after Smith departed, cutting the Bills' lead to 17-12.

The Jets' quarterback, who had played every offensive snap in the first nine games, took a physical beating. Late in the first half, he was sandwiched by a pair of Buffalo defenders and wound up missing the first series of the third quarter due to a concussion evaluation.

He was cleared and returned for one series before the ankle injury.

It was Klubnik's NFL debut. The former Clemson star, a fourth-round pick, was the No. 2 quarterback for every game but saw no game action.