Deion Sanders had been on the hot seat as his Colorado football team was in the midst of their second disappointing season in a row. After going just 3-9 last season, the Buffaloes were 3-6 heading into their matchup against No. 14 Houston, which still had hopes of making the 12-team College Football Playoff.

However, Sanders and his Colorado team might have nuked the Cougars' CFP chances after a shock 42-32 win, the biggest of Sanders' stint to date. Per Yahoo Sports, it was the Buffs' highest-ranked win since 2017, when they beat No. 3 Oklahoma.

THE BIGGEST WIN OF THE DEION SANDERS ERA ‼️

Colorado's 42-32 win over No. 14 Houston is its first win over a top-15 team since it defeated No. 3 Oklahoma in September 2007 😱 pic.twitter.com/LqHkfXSGZ3

— Yahoo Sports (@YahooSports) November 14, 2026

The Buffaloes went absolutely berserk on the ground, rushing for 249 yards with five touchdowns. Three of those touchdowns came in a wild second quarter, when they scored on three 30-plus yard runs.

Senior running back Richard Young led the charge with 99 yards on 21 carries with two scores. Young was also instrumental in their big 27-24 overtime win over Kansas State last month. He had 120 yards on 24 carries with two touchdowns in that game.

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With his huge win over Houston, Deion Sanders may have bought himself a bit more time in Boulder. This season has been one to forget, with humiliating losses to Texas Tech and Oklahoma State springing to mind.

However, they did give Utah, unbeaten at 9-0 and the current No. 2 team in the nation, its closest game of the season when they squeezed past the Buffs 27-24 in Boulder. That result, coupled with the Houston upset, will give Colorado fans hope that Coach Prime still has enough juice to turn the flagging program around.