The San Francisco 49ers have some offensive injury worries. But they also have things that are going well. However, on the defensive side, the injuries keep piling up for Nick Bosa. He missed practice again, according to a post on X by Matt Barrows.

“An injury where the 49ers can least afford it: Nick Bosa missed Wednesday's practice with a “knee/resting player” designation. He missed Thursday's with a calf issue.”

Bosa, 28, is an eight-year NFL veteran. He played full seasons from 2021-23. However, he played in only 14 games in 2024 and three last year. In his career, he has 64.5 sacks. The 49ers are 2-0 as they play host to the Cardinals on Sunday.